DNA

With deep sorrow we report the news of the passing of Mariel Vazquez on July 5, 2026, at the age of 55. Mariel was an esteemed applied mathematician and an internationally recognized member of the scientific community. She was well known for applying knot theory and topology to DNA and influencing the development of the field of DNA topology. Mariel leaves behind a distinguished academic career and a trail of devoted students and collaborators.

Your DNA contains the genetic blueprint necessary to not just build your body but to build the proteins and molecules that ensure your body’s functionality. DNA encodes RNA, RNA encodes proteins and voila, your body functions. 

But the biological reality of this process is much more complex. The shapes, twists and entanglements of your DNA and RNA— their topology — influence their functionality and your health. Damage to DNA, like radiation exposure leading to double-strand breaks, can cause mutations that develop into diseases like cancer.